Anti phospholipid syndrome

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Neurological manifestations of anti-phospholipid (Hughes) syndrome.

In the 21 years since the description of the antiphospholipid syndrome (APS), neurological features have become recognised as some of the most important and common aspects of the syndrome. Recognition of the relationship between APS and central nervous system impairment could open the door to improved treatment and outcomes in some neurological syndromes.

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GAPSS: the Global Anti-Phospholipid Syndrome Score.

OBJECTIVE To develop and validate a risk score [global APS score (GAPSS)] derived from the combination of independent risk for thrombosis and pregnancy loss (PL), taking into account the aPL profile, conventional cardiovascular risk factors and the autoimmune antibody profile. METHODS This cross-sectional study included 211 consecutive SLE patients. Data on clinical manifestations, convention...

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Is clubbing a feature of the anti-phospholipid antibody syndrome?

A patient with the anti-phospholipid antibody syndrome and digital clubbing is described. No recognized cause for the clubbing was found. It is suggested that platelet aggregation and microthrombi formation as a result of anti-phospholipid antibody may be involved in the pathogenesis of the digital clubbing. This may be a new feature of the anti-phospholipid antibody.

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Anti-phospholipid syndrome in Nigeria: report of five cases.

Five cases of secondary anti-phospholipid syndrome (APS) are presented and literature reviewed. Pregnancy loss was the most common presentation but neurologic manifestations are also seen. IgG ACA was more commonly seen than IgM ACA. Although APS has been infrequently reported in black Africans, an awareness of this condition is needed especially among females with previous recurrent pregnancy ...

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The global anti-phospholipid syndrome score in primary APS.

OBJECTIVE The aim of this study was to evaluate the clinical relevance of the global APS score (GAPSS) in a cohort of primary APS patients. METHODS This study included 62 consecutive patients with primary APS. Data on clinical manifestations, conventional cardiovascular risk factors and aPL profile were collected. The GAPSS was calculated for each patient by adding together the points corresp...

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ژورنال

عنوان ژورنال: European Journal of Vascular and Endovascular Surgery

سال: 1995

ISSN: 1078-5884

DOI: 10.1016/s1078-5884(05)80159-5